Biloxi sits where the Mississippi Sound meets a city shaped by centuries of Gulf Coast history, a strong military presence, and a casino industry that transformed the waterfront in the early 1990s. Keesler Air Force Base anchors a significant portion of the local economy and places Biloxi among Mississippi's most strategically important cities. As the fourth-largest city in the state and a principal hub of the Gulfport-Biloxi metro area, it carries a weight well beyond its roughly 50,000 residents.
Neighborhoods here run the range from the walkable Downtown corridor near the historic Biloxi Lighthouse and MGM Park to the marina-side character of Point Cadet and East Biloxi, the suburban ease of North Biloxi along the Popps Ferry corridor, and the retail-connected West Biloxi area near the Mississippi Coast Coliseum. The Ohr-O'Keefe Museum of Art, designed by Frank Gehry, gives the city a striking cultural landmark that draws visitors from across the region.