Tacony-Wissinoming sits next to I-95, the Delaware River, and directly across from the Tacony-Palmyra bridge into New Jersey. Most locals use cars to get around due to the proximity of major highways and the ease of street parking. Also, many apartments for rent include parking. Some residents even work in New Jersey and the northern suburbs due to the convenient location. The SEPTA Regional Rail and several bus routes also service the area.

Although Tacony-Wissinoming is located only 10 miles away from Center City, the town itself has plenty of fun and food to offer. Besides its retailers, it also hosts the "Hoagie Trail," a cluster of old-school Philly sandwich shops. Check out DeNofa's Deli, a family-owned business that serves fresh Italian meats and house-made sausage. Work off your meal at the Tacony Creek Trail, located in the beautiful Tacony Park. The creek allows fishing and swimming for a taste of country living.