Mesa Grande's history dates back two thousand years to the time of the Hohokam Indians. The tribe, whose name roughly translates to "The Departed Ones," constructed the original 125-mile city canal formation that’s still in use today. In the late 1800s, U.S. Army troops fought the Apache off the land, opening the way for Western settlement.
After World War II, the community witnessed a significant boost in development as many military
families decided to settle in the area. Up until the late 1960s, more than 50 percent of the residents earned their income directly from farming. However, the tail end of the 20th century saw a massive increase in technology companies and health facilities, opening jobs in other sectors.
Mesa Grande teems with cultural spirit and exuberant art. Over 200 sculptures line the streets of downtown, and many art galleries and successful artist studios have opened throughout the area.