South San Francisco, known locally as "South City," sits between San Bruno Mountain and San Francisco Bay. Once an industrial center, it's now home to numerous biotechnology companies. The rental market offers options at various price points, with average rents ranging from $2,432 for studios to $4,068 for three-bedroom apartments.
The city's downtown along Grand Avenue features independent shops and local eateries that contribute to its community atmosphere. Sign Hill Park, home to the historic "South San Francisco The Industrial City" sign, provides hiking trails with sweeping views of the bay. Orange Memorial Park offers recreational facilities, including a swimming pool and seasonal farmers' market. East of Highway 101, the city has developed into a biotechnology research center, with Genentech's campus serving as a major employer.
