Southside Flats is one of two neighborhoods that make up Pittsburgh's dynamic Southside. The primarily residential neighborhood is located at the base Mount Washington, Southside's enormous hill. It also sits right under the Southside Slopes, the other Southside neighborhood, which runs precariously up the hillside. Residents of the Flats have convenient access to the hottest shopping and nightlife district in Pittsburgh, as well as riverfront trails and parks.

The lively neighborhood lies south of the Monongahela River and south of East Carson Street, known as the "Great American Main Street." One of Pittsburgh's major commercial corridors, East Carson Street offers 15 blocks of Victorian architecture, boutiques, restaurants, bars, art galleries, theatres, and live music venues.

Southside has experienced a residential renaissance, as older 19th-century homes, abandoned factories, and mills are being renovated into modern houses, apartments, and luxury lofts.